Biotechnology (CBSE Sample Paper Class XII)

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Download CBSE Biotechnology Sample Paper Class XII (12th) 2009

Sample Paper 2009

Biotechnology

Class XII

[set-1]

 

SECTION-A

 

  1. What are prions? Name a  disorder caused by prions.
  2. Name two diseases caused by the absence of a protein. Thallasaemia,
  3. Name the enzyme whose deficiency leads to “SCID” in children.
  4. Name the source organism of subtilisin.
  5. Why the bacteriophage vectors are not required any specific treatment of host cell to introduce foreign DNA into cultured cell?
  6. Name the phenomenon of invitro heat treatment of meristem.

      7. What is the single letter IUPAC code for?

                   a.Tryptophan.

       b.Serine

 SECTION-B

 

  1. You wish to introduce the human insulin gene into a bacterial host in the hope of producing large amounts of human insulin. Should you use genomic DNA or cDNA ? Explain.

 

  1. Who first developed the protein sequencing method? Name the protein to be sequence first. Sanger. Isulin was the 1st protein 2 b sequenced.

 

  1. Name the first sequenced and who developed the method of sequencing.
  2. What do you mean by term probiotics?
  3. What role is played by hydrophobic forces in proteins?
  4. What is a restriction enzyme? Write the types of restriction enzyme. Those enzymes which restrict the growth of any forein body [virus, DNA] in a bacterial cell are called restriction enzymes.
  5. What are ESTs ? How are they useful in genome analysis ?
  6. What are (RE) restriction end nucleases? Why are they called as molecular scissors? 

SECTION-C

 

  1. Differentiate between the characteristics of normal cells & cancerous cells?
  2. What is OKT-3 ? Why is it administered to patients undergoing organ transplantation ? What is the relevance of fusing an antibody producing B-cell with myeloma cells in hybridoma technology ?
  3. Explain DNA Microarray technology? Write its main applications
  4. Define protein finger database. And write their importance.
  5. Define and explain peptide mapping by illustrating the example of sickle cell anemia.

SECTION-D

 

  1. What is a Microarray? Name and explain the Microarray technique used to distinguish a normal cell from a diseased one.

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